The contribution of Giovanni Luca Durazzo was decisive for the purchase of the building in via Balbi in 1679 by his brother Eugenio. Among the various positions in the service of the Republic, Giovanni Luca held for the second time in the two-year period 1669-1670 that of Genoese ambassador at the papal court. During that stay in Rome, most likely, the execution of the extraordinary painting by the Flemish painter, one of the major portrait painters of the Roman nobility in the second half of the seventeenth century, fell. The Genoese patrician wears a Venetian lace tie, a black jacket embellished with an elegant lace fringe and a wig of brown curls according to the dictates of late Louis XIV fashion. The penetrating vividness of the expression, the gaze that inclines to smile, the refined technique, make it one of the highest quality portraits in the collection of the Genoese museum.